Pre-implantation Genetic Screening (PGS)
PGS checks the number of chromosomes in each embryo at the blastocyst stage (a blastocyst is an embryo that has been developed in the laboratory for five or six days after fertilisation).
Because many blastocysts have the wrong number of chromosomes (a condition known as aneuploidy), PGS is a powerful tool for selecting a good embryo for transfer. Aneuploidy can lead to miscarriages, birth defects and other complications.
Benefits of PGS:
- if you have a normal/euploid embryo, then it has the same chance of implanting regardless of your age.
- Lower miscarriage rate
- More certainty for people about the likely outcome of treatment.
Who can particularly benefit from PGS?
- Women aged 38 and over.
- Women who have had recurrent miscarriages.
- Women who have not become pregnant despite the transfer of several embryos.
How PGS works:
- About 5-6 cells are biopsied from each blastocyst using a fine glass needle.
- The blastocysts are frozen for later use.
- The cells are sent to a specialist genetic laboratory for analysis.
- Chromosomally normal blastocysts are transferred at a later date after thawing.
Useful to know
- Embryo selection with PGS does not increase the overall chance of a baby from all the embryos available, but it can reduce the time to pregnancy by giving a better choice of which embryo to use first.
The Cost of PGS
The fees for using PGS are covered in our fees section.
- The PGS fee is a per embryo charge and covers the embryo biopsy and testing from the IVF cycle.
- To do PGS you will need to have frozen embryo transfers to use suitable embryos. The costs of these are separate to the cost of the PGS testing.
PGS - What, how and who can benefit from PGS
An explanation of why you may want to take the path of pre-implantation genetic screening on your fertility journey, and what the results might mean.
PGS - Thawing an embryo for PGS and the results
This video describes the journey for an embryo during the process of thawing for pre-implantation genetic screening, and what the results of this analysis might mean.
Support every step of the way
Genetic Services is now available in Auckland to help provide information and support - on the relevance, availability and potential outcomes of genetic testing and known genetic disorders.
Our embryologists are implementing the latest fertility technologies, with leadership from Dean Morbeck, Scientific Director.